Journal articles can be used to find original research studies, as well as systematic reviews and meta-analyses.
The type of question is important and can help lead you to the best study design. To limit your search to a specific study design, use the database's filters/limits or add keywords to your search (e.g., lung cancer AND cohort).
|Type of Question||Best Type of Study|
|Therapy||RCT -> cohort -> case control -> case series|
|Diagnosis||prospective, blind comparison to a gold standard
|Etiology/Harm||RCT -> cohort -> case control -> case series|
|Prognosis||Cohort study -> case control -> case series|
|Prevention||RCT -> cohort study -> case control -> case series|